When we think of protecting our skin from sun damage and any environmental
aggressors, the first thing that usually comes to mind is sunscreen. And
coating ourselves with the highest SPF possible to try and shield us from
the sun’s damaging rays. Most dermatologists agree that UV exposure is one
of the leading causes of aging. While sunscreen is a very important part of
any good daily skin care routine, it’s not enough.
Here’s the thing about aging- it also happens on a cellular level. Anything
we do to protect ourselves from the elements on the outside, isn’t enough
to stop us from aging on the inside.
We all age- it’s inevitable. And while we haven’t been able to
stop time, there are certain things we can do to try and slow it down.
That’s where stem cells come into play. Our stem cells are released through
our bone marrow to repair and renew our tissue throughout our bodies. But
what are stem cells and how can they help us with the aging skin?
Stem cells are a class of undifferentiated cells that can differentiate
into specific cell types. Most human stem cells come from these two
sources- embryonic stem cells and adult stem cells. Embryonic stem cells
are derived from a human embryo. Adult (somatic) stem cells, are throughout
the human body and are found in different types of tissue- like the brain,
bone marrow, blood vessels, liver and skin.
When we were infants, we each had an adult stem cell circulation of 100% in
our blood stream. That meant that if we had any injury or illness, our
systems would release stem cells to heal and repair everything quickly. Our
adult stem cell release was at optimal functioning level then. Now as
adults, that same release rate has dropped considerably.
· At 35 years – stem cell release rate drops by 45%
· At 50 years- stem cell release rate drops by 50%
· At 65 years- stem cell release rate drops by 90%
These release rates mean one thing- you are unable to effectively repair
and renew skin that is compromised by time and the environment.
Stem cells are a very important factor in not just how we age, but
how well we do it. Stem cells need growth factors within their own
environment to stimulate cell proliferation (cell growth and production).
The older we get, the more our cellular activity, or stem cell release
rate- naturally slows down. This leaves us with fewer healthy cells to
rebuild and regenerate our skin, compromising our epidermal layer (skin’s
surface) and leaving our precious DNA exposed and unprotected from UV
induced damage and oxidative stress.
Once our skin can no longer defend against these environmental factors,
skin aging is accelerated at a much faster rate. What are the
signs of this kind of damage-induced aging? Thinning, sagging and laxity
(loss of firmness) to the skin’s structure.
Stem cells and growth factors work together to stimulate the production of
new, healthy skin cells, and help to repair damage done to existing cells.
Now the epidermal layer of our skin can once again be the protective
barrier that effectively defends our skin against the UV damage and
cellular oxidation we encounter daily.
Over time, our skin can regain its youthful structure and appearance-
restoring the density, firmness and elasticity that give us back the
younger-looking skin we want; while regenerating the fresh, healthy cells
we need. Utilizing stem cells can be the key to rejuvenating your skin and
restoring a youthful appearance; but where the stem cells are
sourced can affect the level of your anti-aging results.
Lots of skin care brands have their own version of stem cell serums or
creams. That does not mean that because they all contain stem cells, they
all work identically and can deliver the same results. It’s where these
stem cells come from that really matters. There are a few different types
of stem cells and knowing the best type to choose for your skin, can make
all the difference.
The first type are human stem cells. A few skin care brands choose to use
human stem cells in their anti-aging products. Most of these serums and
creams are extremely expensive because it harder to source large amounts of
human stem cells and may be considered controversial; as some brands use
embryonic stem cells and some use adult stem cells. It may be hard to know
exactly which of these sources were used in the product.
The second type of stem cells more commonly used in stem cell anti-aging
products, are plant stem cells. While more readily available and less
expensive, the cell-signaling that occurs between plant stem cells can
release growth factors to stimulate their regeneration, healing
and cell growth. It is not the same cell-signaling
biochemical language of human stem cells. This means that plant stem cells
cannot effectively stimulate human skin cells for renewal. This
makes plant stem cells a much less effective anti-aging option.
The third type of stem cells are mammalian-derived. These stem cells are
much closer to human stem cells and offer the same cell regenerating,
repairing and anti-aging benefits. Mammalian-derived stem cells are also
easier to source; this means that the concentration of stem cells can be a
lot higher than a formula that uses human stem cells. Mammalian-derived
stem cells are also biocompatible within human skin- letting you experience
all the anti-aging benefits that stem cells can offer.
Mammalian-derived stem cells can regenerate, repair and restore
younger-looking skin and help to return its youthful response- skin looks and acts younger. Stem cells are your skin’s defense
- Cellular aging by encouraging repair to older cells compromised by age and the environment
- Regeneration of new, healthy cells to maintain skin structure, density and firmness
- Restoring a compromised epidermal layer (skin’s surface) to defend DNA against breakdown from UV damage
- Strengthens skin to endure and recover from the effects of oxidative stress
- Help to rebuild and stimulate healing on a cellular level within skin tissue
Knowing which type and where your stem cell formula comes from can help you
decide which stem cell anti-aging product is right for you. NeoCorium EGF Stem Cell Anti-Aging Facial Treatment
is one of the first all-natural, mammalian-derived EGF stem cell
concentrates available on the market today.
A multiple growth factor and stem cell facial treatment, NeoCorium’s formula delivers clinical-grade results that rival an in-office EGF
anti-aging facial. Every bioactive ingredient in this EGF stem cell concentrate is a powerful, all-natural anti-aging product.
mammalian-derived EGF stem cell formula stimulates the active growth and
regeneration of resilient, healthy skin to restore a younger appearance.
This advanced proprietary blend of all-natural bioactive ingredients makes NeoCorium EGF Stem Cell Anti-Aging Facial Treatment the
best choice- and the only one you’ll need for your ultimate anti-aging
- Epidermal growth factor
– Clinically decreases wrinkling, aids in improved skin density and
assists in producing new collagen formation within the skin. (Hussain et al., 2008) * see below
- Fibroblast growth factor
– Improves skin softness, viscoelasticity as well as reducing wrinkle
volume and depth. Rejuvenation of aging skin. (Ono, I. 2011) (Zeranska et al., 2016) *see below
- Platelet-derived growth factor
– Encourages healthy cell growth, type 1 collagen and
skin fibroblasts that may maintain skin integrity and youth. (Kim et al., 2011) *see below
– Reparative and rejuvenation for skin tissue. Reduces inflammation and
helps heal. (Sorg et al., 2013) *see below
- Transforming growth factors Alpha & Beta
– Stimulation of collagen secretion and maintaining healthy skin
structure. Enhances the rate of healing damaged skin. (Ching et al., 2011) (Ranaweera, 2011) *see below
-Stimulates immune responses within cells. Reduces inflammation,
enhances healing and activation of growth factors. (Draelos, 2016) *see below
- Insulin-like growth factors 1 & 2
– Increases healing and aids in healthy cell growth, collagen and
elastin. Decreases both intrinsic skin aging (natural aging process)
and extrinsic skin aging (aging from environmental factors). (Povoa et
al., 2011) (Ranaweera, 2011) *see below
- Emu oil
– Anti-inflammatory, has essential omega-3’s, reduces the appearance of
scars and sun damage, penetrates deeply into skin to moisturize, aids
in healing eczema and psoriasis. (Axe, 2016) *see below
- Jojoba oil
– Promotes the absorption of topicals, anti-inflammatory properties,
moisturizing, can reduce the signs of aging, aids in wound healing and
protecting the skin. (Pazyar et al., 2013) *see below
- Lavender oil
– Aids in increasing fibroblasts to synthesize rapid collagen
production and stimulates healing at a faster rate. (Mori et al., 2016) *see below
**Not all human clinical trials- some in vivo, in vitro, in animal models**