March 14, 2017

Stem Cells – Your Skin’s First Line of Anti-Aging Defense

When we think of protecting our skin from sun damage and any environmental
aggressors, the first thing that usually comes to mind is sunscreen. And
coating ourselves with the highest SPF possible to try and shield us from
the sun’s damaging rays. Most dermatologists agree that UV exposure is one
of the leading causes of aging. While sunscreen is a very important part of
any good daily skin care routine, it’s not enough.

Here’s the thing about aging- it also happens on a cellular level. Anything
we do to protect ourselves from the elements on the outside, isn’t enough
to stop us from aging on the inside.

We all age- it’s inevitable. And while we haven’t been able to
stop time, there are certain things we can do to try and slow it down.
That’s where stem cells come into play. Our stem cells are released through
our bone marrow to repair and renew our tissue throughout our bodies. But
what are stem cells and how can they help us with the aging skin?

Stem cells are a class of undifferentiated cells that can differentiate
into specific cell types. Most human stem cells come from these two
sources- embryonic stem cells and adult stem cells. Embryonic stem cells
are derived from a human embryo. Adult (somatic) stem cells, are throughout
the human body and are found in different types of tissue- like the brain,
bone marrow, blood vessels, liver and skin.

When we were infants, we each had an adult stem cell circulation of 100% in
our blood stream. That meant that if we had any injury or illness, our
systems would release stem cells to heal and repair everything quickly. Our
adult stem cell release was at optimal functioning level then. Now as
adults, that same release rate has dropped considerably.

· At 35 years – stem cell release rate drops by 45%

· At 50 years- stem cell release rate drops by 50%

· At 65 years- stem cell release rate drops by 90%

These release rates mean one thing- you are unable to effectively repair
and renew skin that is compromised by time and the environment.

Stem cells are a very important factor in not just how we age, but
how well we do it. Stem cells need growth factors within their own
environment to stimulate cell proliferation (cell growth and production).
The older we get, the more our cellular activity, or stem cell release
rate- naturally slows down. This leaves us with fewer healthy cells to
rebuild and regenerate our skin, compromising our epidermal layer (skin’s
surface) and leaving our precious DNA exposed and unprotected from UV
induced damage and oxidative stress.

Once our skin can no longer defend against these environmental factors,
skin aging is accelerated at a much faster rate. What are the
signs of this kind of damage-induced aging? Thinning, sagging and laxity
(loss of firmness) to the skin’s structure.

Stem cells and growth factors work together to stimulate the production of
new, healthy skin cells, and help to repair damage done to existing cells.
Now the epidermal layer of our skin can once again be the protective
barrier that effectively defends our skin against the UV damage and
cellular oxidation we encounter daily.

Over time, our skin can regain its youthful structure and appearance-
restoring the density, firmness and elasticity that give us back the
younger-looking skin we want; while regenerating the fresh, healthy cells
we need. Utilizing stem cells can be the key to rejuvenating your skin and
restoring a youthful appearance; but where the stem cells are
sourced can affect the level of your anti-aging results.

Lots of skin care brands have their own version of stem cell serums or
creams. That does not mean that because they all contain stem cells, they
all work identically and can deliver the same results. It’s where these
stem cells come from that really matters. There are a few different types
of stem cells and knowing the best type to choose for your skin, can make
all the difference.

The first type are human stem cells. A few skin care brands choose to use
human stem cells in their anti-aging products. Most of these serums and
creams are extremely expensive because it harder to source large amounts of
human stem cells and may be considered controversial; as some brands use
embryonic stem cells and some use adult stem cells. It may be hard to know
exactly which of these sources were used in the product.

The second type of stem cells more commonly used in stem cell anti-aging
products, are plant stem cells. While more readily available and less
expensive, the cell-signaling that occurs between plant stem cells can
release growth factors to stimulate their regeneration, healing
and cell growth. It is not the same cell-signaling
biochemical language of human stem cells. This means that plant stem cells
cannot effectively stimulate human skin cells for renewal. This
makes plant stem cells a much less effective anti-aging option.

The third type of stem cells are mammalian-derived. These stem cells are
much closer to human stem cells and offer the same cell regenerating,
repairing and anti-aging benefits. Mammalian-derived stem cells are also
easier to source; this means that the concentration of stem cells can be a
lot higher than a formula that uses human stem cells. Mammalian-derived
stem cells are also biocompatible within human skin- letting you experience
all the anti-aging benefits that stem cells can offer.

Mammalian-derived stem cells can regenerate, repair and restore
younger-looking skin and help to return its youthful response- skin looks and acts younger. Stem cells are your skin’s defense
shield against:

  • Cellular aging by encouraging repair to older cells compromised by age and the environment
  • Regeneration of new, healthy cells to maintain skin structure, density and firmness
  • Restoring a compromised epidermal layer (skin’s surface) to defend DNA against breakdown from UV damage
  • Strengthens skin to endure and recover from the effects of oxidative stress
  • Help to rebuild and stimulate healing on a cellular level within skin tissue

Knowing which type and where your stem cell formula comes from can help you
decide which stem cell anti-aging product is right for you. NeoCorium EGF Stem Cell Anti-Aging Facial Treatment

is one of the first all-natural, mammalian-derived EGF stem cell
concentrates available on the market today.

A multiple growth factor and stem cell facial treatment, NeoCorium’s formula delivers clinical-grade results that rival an in-office EGF
anti-aging facial
. Every bioactive ingredient in this EGF stem cell concentrate is a powerful, all-natural anti-aging product.

NeoCorium’s
mammalian-derived EGF stem cell formula stimulates the active growth and
regeneration of resilient, healthy skin to restore a younger appearance.
This advanced proprietary blend of all-natural bioactive ingredients makes NeoCorium EGF Stem Cell Anti-Aging Facial Treatment the
best choice- and the only one you’ll need for your ultimate anti-aging
solution.

Bioactive Ingredients:

  • Epidermal growth factor
    – Clinically decreases wrinkling, aids in improved skin density and
    assists in producing new collagen formation within the skin. (Hussain et al., 2008) * see below
  • Fibroblast growth factor
    – Improves skin softness, viscoelasticity as well as reducing wrinkle
    volume and depth. Rejuvenation of aging skin. (Ono, I. 2011) (Zeranska et al., 2016) *see below
  • Platelet-derived growth factor
    – Encourages healthy cell growth, type 1 collagen and
    skin fibroblasts that may maintain skin integrity and youth. (Kim et al., 2011) *see below
  • Erythropoietin
    – Reparative and rejuvenation for skin tissue. Reduces inflammation and
    helps heal. (Sorg et al., 2013) *see below
  • Transforming growth factors Alpha & Beta
    – Stimulation of collagen secretion and maintaining healthy skin
    structure. Enhances the rate of healing damaged skin. (Ching et al., 2011) (Ranaweera, 2011) *see below
  • Interleukins
    -Stimulates immune responses within cells. Reduces inflammation,
    enhances healing and activation of growth factors. (Draelos, 2016) *see below
  • Insulin-like growth factors 1 & 2
    – Increases healing and aids in healthy cell growth, collagen and
    elastin. Decreases both intrinsic skin aging (natural aging process)
    and extrinsic skin aging (aging from environmental factors). (Povoa et
    al., 2011) (Ranaweera, 2011) *see below
  • Emu oil
    – Anti-inflammatory, has essential omega-3’s, reduces the appearance of
    scars and sun damage, penetrates deeply into skin to moisturize, aids
    in healing eczema and psoriasis. (Axe, 2016) *see below
  • Jojoba oil
    – Promotes the absorption of topicals, anti-inflammatory properties,
    moisturizing, can reduce the signs of aging, aids in wound healing and
    protecting the skin. (Pazyar et al., 2013) *see below
  • Lavender oil
    – Aids in increasing fibroblasts to synthesize rapid collagen
    production and stimulates healing at a faster rate. (Mori et al., 2016) *see below

**Not all human clinical trials- some in vivo, in vitro, in animal models**

References

  1. http://dx.doi.org/10.1080/14764170701885392
  2. https://doi.org/10.5114/pdia.2014.44024
  3. https://doi.org/10.5021/ad.2011.23.4.424
  4. https://www.ncbi.nlm.nih.gov/articles/22430919/
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212033/
  6. https://books.google.com/books?id=MCW1CgAAQBAJ&lpg=PA320&ots=A4AybX7sPV&dq=interleukins%20for%20skin%20rejuvenation&pg=PA321#v=onepage&q=interleukins%20for%20skin%20rejuvenation&f=false
  7. https://www.ncbi.nlm.nih.gov/pubmed/22281905
  8. https://www.dermnetnz.org/topics/role-of-growth-factors-in-skin-creams
  9. https://draxe.com/emu-oil/
  10. https://www.ncbi.nlm.nih.gov/pubmed/?term=24442052%5Buid%5D
  11. https://dx.doi.org/10.1186/s12906-016-1128-7
  12. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842382/
  13. http://ag-usa.net/pgs-plantgrowthhormones.htm
  14. https://www.dermnetnz.org/topics/role-of-growth-factors-in-skin-creams
  15. http://www.stemcellnutrition.net/anti-aging-and-adult-stem-cells
March 4, 2017

How Epidermal Growth Factors (EGF) Anti-Aging Effects Can Renew Your Appearance

EGF

Every year it seems we hear about a new beloved skin care ingredient that
promises to better and more effective than the one everyone was raving
about the year before. This is officially the year of EGF
also known as epidermal growth factor. This new, trendy
ingredient is all over the internet in beauty blogs, skin care ads and
YouTube channels. Except that it’s not new at all.

EGF
(epidermal growth factor)
has been around for quite a while. And scientists are continually testing EGF to see what other applications this amazing growth
factor has. What exactly is epidermal growth factor and what can it do for you?

Epidermal growth factor
is a polypeptide that stimulates cell growth and division. It also plays a
very important role in the wound healing process- everything from sun
damage, burns, scarring and wrinkles- EGF has the
incredible ability to jumpstart the skin by regenerating new, healthy skin
at the cellular level. It can also stimulate collagen production deep
within the dermal layer of the skin, which can restore lost volume and
firmness to skin’s structure.

Our bodies produce growth factors naturally when we are young. As we grow
past puberty, our bodies produce less and less of these precious
polypeptides and our cellular growth and division slows down as well. What
does this mean? It means we are aging. Inside and out. Our skin is
usually just the first place we notice it. We need growth factors to renew
our cells and tissue to stay healthy and heal quickly.

We don’t just need epidermal growth factor, either. Growth
factor families are in the hundreds. Each family consists of groups of
growth factors that work together for a specific purpose. In fact, no
individual growth factor can solely “do it all” for our skin, or anywhere
else in our bodies. Growth factors work best and most effectively when they
are paired up with other ones. Like EGF and IGF-1 & 2, as an example.

In fact, to be the most effective on our aging skin, we need several types of growth factors working synergistically to see the
maximum results these fantastic factors can have on making our skin
youthful and healthy again.

The addition of EGF to skin care products is an anti-aging
break through. But the very best skin care products will have more than
just one type of growth factor in their formula. Our skin needs cellular
growth and division of those new cells for fresh, healthy skin to surface.
This is also why the type of EGF is important.
There are several types of EGF that have been added to
today’s skin care products. Some of these types of EGF
products are making claims that not entirely true with respect to what they
can do for your skin.

The first type is human EGF (epidermal growth factor). We
produce this naturally in our bodies; our levels of this type of growth
factor drop significantly after puberty. Some skin care products contain
trace amounts of this growth factor. But because it’s harder to source and
may be considered controversial for use; it may be hard to know where and
how this type of growth factor was obtained for use in a product. It’s also
the most expensive- costing several hundred dollars for trace amounts of
this type of EGF.

The second type of EGF is plant-derived. This type is much
easier to source, because they can be “farmed” for commercial use.
Unfortunately, the growth hormones plants produce regulate their
growth cycle, water absorption, seed dormancy, root growth and fruit
ripening. Plant growth hormones do not sufficiently stimulate the
biochemical signals with human skin to regenerate and repair our skin
cells. This makes formulas with plant-derived growth hormones a much less
effective choice for anti-aging.

The third type is mammalian-derived EGF. These growth
factors are a lot closer to human growth factors and offer the same cell
regenerating, anti-aging benefits. Mammalian-derived EGF
is also easier to source; this means the concentration of growth factors
can be a lot higher than a formula who uses human growth factors, which are
usually much more expensive and with a lower concentration ofEGF overall. They are alsobiocompatible within human skin- that means you can experience all the wonderful anti-aging benefits that growth factors can
have.

Now that you know the different types of epidermal growth factors, let’s talk about what those
benefits are. With the right groups of growth factors working together
within your skin, every sign of aging is addressed. Growth factors work
within your skin to:


  • promote the increased production of collagen and elastin for
    maintaining skin’s structure
  • increase skin density (thickness)
  • decrease enlarged pores
  • improve uneven skin tone and pigmentation
  • improve skin texture and softness
  • decrease wrinkling due to new collagen synthesis
  • improve skin smoothness and firmness
  • increase elasticity and volume

EGF
and a balanced mixture of other growth factors are crucial and the key to
keeping skin youthful and healthy by “feeding” your skin on a cellular
level.

Finding the best epidermal growth factor products is much easier if you
know what to look for. Remember, the most effective ones will use
mammalian-derived growth factors to give your skin the maximum anti-aging
benefits by using a higher concentration of epidermal growth factor.

The formula that you choose should also have more than one growth factor in
it. Growth factors work best when they are grouped together to maximize
skin cell regeneration and repair. NeoCorium EGF Stem Cell Anti-Aging Facial Treatment is a
skin care product that uses 4500 cc of only
mammalian-derived EGF and 9 other growth factors and stem cells in a concentrated,
all-natural formula. This facial treatment formula delivers the
clinical-grade results that you would get at an in-office EGF facial. Every ingredient in this concentrated formula
is there for a reason- each one is a powerful anti-ager.

The bioactives in NeoCorium’s EGF Stem Cell Anti-Aging Facial Treatment are
all-natural, ethically sourced and made in the USA- making this anti-aging
formula a top choice.

Bioactive Ingredients:

  • Epidermal growth factor
    – Clinically decreases wrinkling, aids in improved skin density and
    assists in producing new collagen formation within the skin. (Hussain et al., 2008) * see below
  • Fibroblast growth factor
    – Improves skin softness, viscoelasticity as well as reducing wrinkle
    volume and depth. Rejuvenation of aging skin. (Ono, I. 2011) (Zeranska et al., 2016) *see below
  • Platelet-derived growth factor
    – Encourages healthy cell growth, type 1 collagen and
    skin fibroblasts that may maintain skin integrity and youth. (Kim et al., 2011) *see below
  • Erythropoietin
    – Reparative and rejuvenation for skin tissue. Reduces inflammation and
    helps heal. (Sorg et al., 2013) *see below
  • Transforming growth factors Alpha & Beta
    – Stimulation of collagen secretion and maintaining healthy skin
    structure. Enhances the rate of healing damaged skin. (Ching et al., 2011) (Ranaweera, 2011) *see below
  • Interleukins
    -Stimulates immune responses within cells. Reduces inflammation,
    enhances healing and activation of growth factors. (Draelos, 2016) *see below
  • Insulin-like growth factors 1 & 2
    – Increases healing and aids in healthy cell growth, collagen and
    elastin. Decreases both intrinsic skin aging (natural aging process)
    and extrinsic skin aging (aging from environmental factors). (Povoa et
    al., 2011) (Ranaweera, 2011) *see below
  • Emu oil
    – Anti-inflammatory, has essential omega-3’s, reduces the appearance of
    scars and sun damage, penetrates deeply into skin to moisturize, aids
    in healing eczema and psoriasis. (Axe, 2016) *see below
  • Jojoba oil
    – Promotes the absorption of topicals, anti-inflammatory properties,
    moisturizing, can reduce the signs of aging, aids in wound healing and
    protecting the skin. (Pazyar et al., 2013) *see below
  • Lavender oil
    – Aids in increasing fibroblasts to synthesize rapid collagen
    production and stimulates healing at a faster rate. (Mori et al., 2016) *see below


**Not all human clinical trials- some in vivo, in vitro, in animal
models**

References

  1. http://dx.doi.org/10.1080/14764170701885392
  2. https://doi.org/10.5114/pdia.2014.44024
  3. https://doi.org/10.5021/ad.2011.23.4.424
  4. https://www.ncbi.nlm.nih.gov/articles/22430919/
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212033/
  6. https://books.google.com/books?id=MCW1CgAAQBAJ&lpg=PA320&ots=A4AybX7sPV&dq=interleukins%20for%20skin%20rejuvenation&pg=PA321#v=onepage&q=interleukins%20for%20skin%20rejuvenation&f=false
  7. https://www.ncbi.nlm.nih.gov/pubmed/22281905
  8. https://www.dermnetnz.org/topics/role-of-growth-factors-in-skin-creams
  9. https://draxe.com/emu-oil/
  10. https://www.ncbi.nlm.nih.gov/pubmed/?term=24442052%5Buid%5D
  11. https://dx.doi.org/10.1186/s12906-016-1128-7
  12. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842382/
  13. http://ag-usa.net/pgs-plantgrowthhormones.htm
  14. https://www.dermnetnz.org/topics/role-of-growth-factors-in-skin-creams
January 27, 2017

Clinical-Grade EGF Stem Cell Facial Treatment Available for In-Home Use from NeoCorium

TAMPA, FL / ACCESSWIRE / January 26, 2017 / NeoCorium, LLC announces that they are releasing their Skin Rejuvenating Facial Treatment to the public. This Clinical-grade EGF and Stem Cell Facial Treatment was previously only available through medical practitioners. Now NeoCorium is giving everyone the ability to experience the power of invasive in-office treatments, in the comfort of their own homes.

“This is a breakthrough for anyone that wants clinical anti-aging results without having to see a dermatologist. NeoCorium’s Skin Rejuvenating Facial Treatment is truly the future of anti-aging skin care,” said Jennifer Aldrich, Director of Communications at NeoCorium, LLC.

The multiple growth factors and stem cells in NeoCorium’s formula self-adjust and adapt to everyone’s individual skin issues; repairing and regenerating new, healthy skin where it’s needed most. This “smart” skin treatment knows how to hydrate, firm, lift, plump and smooth the skin to return youthful response- which means skin looks and acts younger. Read more http://finance.yahoo.com/news/clinical-grade-egf-stem-cell-130000510.html

January 14, 2017

New Anti-Aging EGF Stem Cell Treatment Launched by NeoCorium

Tampa, Florida – January 14, 2017 – Today, NeoCorium, LLC. announced the immediate availability of NeoCorium Skin Rejuvenating Treatment. This enables women and men alike to have access to a clinical-grade EGF stem cell treatment; without a visit to their dermatologist.

“NeoCorium Skin Rejuvenating Treatment was designed to give everyone the power of an invasive, in-office procedure, in an all-natural, non-invasive topical treatment. It’s truly the ultimate anti-aging solution,” states Jennifer Aldrich, Director of Communications at NeoCorium, LLC..

Sources at NeoCorium, LLC. state that the anti-aging treatment was inspired through research on the benefits of growth factors and stem cells for an eBook produced for the medical community. It was discovered that the bioactive components in mammalian EGF and stem cells have a powerful effect on rejuvenating aging skin, leading to NeoCorium’s breakthrough creation.

Read more: http://www.digitaljournal.com/pr/3201488#ixzz4WwiSiE8o